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The central nervous system risks may include: altered cognitive function, reduced motor function, and behavioral changes, all of which may affect performance and human health. Late CNS risks may include neurological disorders such as Alzheimer’s disease (AD), dementia and premature aging.

Acute CNS risks include changes in cognition, motor function, behavior, and mood, which may affect performance and human health. Specific examples of human behaviors and cognitive function of interest that may be affected by space flight include short-term memory, learning, spatial orientation, motor function, emotion recognition, risk decision making, vigilance, reaction time, processing speed, circadian regulation, fatigue, and neuropsychological changes.

Consult reports and evidence of human research of NASA “Human Research Roadmap”:

Conflicts of interests

None stated by the authors


None stated by the authors.


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Brain and Microgravity


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